Description

Paulomycin B is a specialized antibiotic compound belonging to the paulomycin family, identified by CAS NO 81988-76-3. This compound is valued for its potent biological activity, particularly against Gram-positive bacteria, making it a critical intermediate and reference standard in antimicrobial research and development. It is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on discovering new therapeutic agents and studying antibiotic mechanisms of action.

Application

• Reference standard for analytical method development and validation in pharmaceutical quality control laboratories.
• Critical intermediate in the research and synthesis of novel antibiotic derivatives and analogs.
• Biological activity screening and mechanism of action studies against resistant bacterial strains.
• Use in microbiological research to study structure-activity relationships (SAR) within the paulomycin class.
• Component in high-throughput screening assays for identifying new antimicrobial leads.
• Preparation of research-grade materials for in-vitro and pre-clinical pharmacological evaluations.

Basic Information

Product Name	Paulomycin B
CAS No.	81988-76-3
Molecular Formula	C35H43NO12
Molecular Weight	669.72 g/mol
Synonyms	Paulomycin B; Antibiotic U-43120; U-43120; NSC 369608; Paulomycin B (Antibiotic U-43120); 4,6-Dideoxy-4-[[(2S,3R,4S,5R,6R)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]amino]-2-O-methyl-D-chiro-inositol 1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 3-(2-methylbut-2-enoyl) ester
EINECS	Contact for details

Quality Control

Our Paulomycin B is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and microbiological assay for potency verification, ensuring it meets the stringent requirements for research applications. Certificates of Analysis (COA) with detailed chromatographic data and batch-specific results are provided.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Microbiological)	≥ 850 µg/mg
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.