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3,15,17-Trihydroxy-5-Androstene CAS NO 81844-76-0


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CAS No.:81844-76-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3,15,17-Trihydroxy-5-Androstene is a hydroxylated derivative of the androstene steroid nucleus, serving as a key intermediate in the synthesis of more complex steroid hormones and pharmaceutical agents. Its specific hydroxylation pattern at the 3, 15, and 17 positions makes it a valuable building block for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on steroid chemistry and endocrinology.

Application

  • Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
  • Research & Development: Used in biochemical and pharmacological research to study steroid hormone pathways, receptor interactions, and metabolic processes.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in steroid analysis using HPLC or LC-MS.
  • Fine Chemical Synthesis: Employed as a specialized starting material for the custom synthesis of labeled compounds (e.g., deuterated or C14-labeled steroids) for tracer studies.

Basic Information

Product Name 3,15,17-Trihydroxy-5-Androstene
CAS No. 81844-76-0
Molecular Formula C19H30O3
Molecular Weight 306.44 g/mol
Synonyms 5-Androstene-3β,15β,17β-triol; 3β,15β,17β-Trihydroxyandrost-5-ene; Androst-5-ene-3β,15β,17β-triol; 15β,17β-Dihydroxy-3β-hydroxyandrost-5-ene; 3,15,17-Trihydroxyandrost-5-ene; 3β,15β,17β-Trihydroxy-5-androstene; (3β,15β,17β)-Androst-5-ene-3,15,17-triol
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Quality Control

Our 3,15,17-Trihydroxy-5-Androstene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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