Description

Carbocyclic 3-Deazaadenosine is a chemically modified nucleoside analog where the nitrogen atom at the 3-position of the adenine ring is replaced by a carbon atom, and the ribose sugar is replaced by a carbocyclic ring. This unique structure makes it a valuable biochemical tool and a key intermediate in medicinal chemistry research, particularly for studying enzyme mechanisms and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and enzyme inhibition studies.

Application

• Biochemical Research: Serves as a critical tool compound for studying the function of S-adenosylhomocysteine (SAH) hydrolase and other methyltransferase enzymes.
• Antiviral Agent Development: Investigated as a potential lead compound or intermediate in the synthesis of novel antiviral drugs, particularly targeting viral replication mechanisms.
• Medicinal Chemistry Intermediate: Used as a sophisticated building block for the synthesis of more complex carbocyclic nucleoside analogs with tailored biological activities.
• Enzyme Inhibition Studies: Acts as a potent inhibitor of certain methyltransferases, useful for probing epigenetic pathways and signal transduction.
• Reference Standard: Employed as a high-purity analytical standard in quality control and method development for pharmaceutical analysis.

Basic Information

Product Name	Carbocyclic 3-Deazaadenosine
CAS No.	81601-33-4
Molecular Formula	C11H14N4O3
Molecular Weight	250.26 g/mol
Synonyms	3-Deazacarbocyclic Adenosine; 3-Deaza-aristeromycin; (±)-Carbocyclic 3-Deazaadenosine; 9-[(1R,2S,3R)-2,3-Dihydroxy-4-cyclopenten-1-yl]-3-deazaadenine; 3-Deaza-C-Ado; c3DAA; 3-Deaza-carba-Ado; NSC 339579
EINECS	Contact for details

Quality Control

Our Carbocyclic 3-Deazaadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.