Description

Bicyclo[2.2.2]Octane-1-Carbonyl Chloride, 4-Propyl- (9Ci) is a specialized bicyclic acid chloride derivative, serving as a high-value synthetic intermediate for constructing complex molecular architectures. Its rigid, three-dimensional bicyclo[2.2.2]octane scaffold is prized for introducing steric bulk and conformational stability into target molecules, which is critical for fine-tuning material properties and biological activity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, high-purity building blocks for drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, sterically defined cores to modulate receptor binding and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the bicyclic structure can enhance photostability and biological efficacy.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and dendrimers with unique thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated chiral ligands and catalysts for asymmetric synthesis.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex natural product analogs.
• Surface Modification Agent: Can be used to functionalize surfaces or nanoparticles, imparting specific chemical reactivity or compatibility.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-1-Carbonyl Chloride, 4-Propyl- (9Ci)
CAS No.	81472-98-2
Molecular Formula	C12H17ClO
Molecular Weight	212.72 g/mol
Synonyms	4-Propylbicyclo[2.2.2]octane-1-carbonyl chloride; 4-Propylbicyclo[2.2.2]octane-1-carboxylic acid chloride; 1-(Chlorocarbonyl)-4-propylbicyclo[2.2.2]octane; 4-n-Propylbicyclo[2.2.2]octane-1-carbonyl chloride; 4-Propylbicyclo[2.2.2]octanecarbonyl chloride; Bicyclo[2.2.2]octane-1-carbonyl chloride, 4-propyl-; 4-Propyl-bicyclo[2.2.2]octane-1-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-1-Carbonyl Chloride, 4-Propyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.