Description

11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Acetate 17-Valerate CAS NO 81456-46-4 is a high-purity steroid intermediate with a complex, multi-functional molecular structure. This compound is critical for pharmaceutical research and development, particularly in the synthesis of advanced corticosteroid analogs. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors seeking reliable, high-quality building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the multi-step synthesis of potent corticosteroid drugs.
• Steroid Research: Used in academic and industrial research to study structure-activity relationships (SAR) of steroid hormones.
• Process Development: Serves as a reference standard or a critical raw material for developing and scaling up new synthetic routes for anti-inflammatory agents.
• Fine Chemical Synthesis: A versatile building block for creating novel chemical entities with potential therapeutic applications.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related steroid compounds.

Basic Information

Product Name	11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Acetate 17-Valerate
CAS No.	81456-46-4
Molecular Formula	C₂₈H₄₀O₇
Molecular Weight	488.62 g/mol
Synonyms	Hydrocortisone 21-Acetate 17-Valerate; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate 17α-valerate; Cortisol 21-acetate 17-valerate; 17α-Valeryloxy-11β,17α,21-trihydroxypregn-4-ene-3,20-dione 21-acetate; Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, 21-acetate 17-(1-oxopentanoate), (11β)-; 11β-Hydroxycortisol 21-acetate 17-valerate
EINECS	Contact for details

Quality Control

Our 11Beta,17,21-Trihydroxypregn-4-Ene-3,20-Dione 21-Acetate 17-Valerate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.