Description

3-Pyridinecarbonyl Chloride, 1,2-Dihydro-6-Methyl-2-Oxo- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its reactive carbonyl chloride group enables efficient coupling reactions, making it invaluable for constructing complex molecular architectures. This high-purity intermediate is primarily sought by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom chemical synthesis services targeting niche markets.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 1,2-Dihydro-6-Methyl-2-Oxo- (9Ci)
CAS No.	81450-66-0
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	6-Methyl-2-oxo-1,2-dihydropyridine-3-carbonyl chloride; 1,2-Dihydro-6-methyl-2-oxo-3-pyridinecarbonyl chloride; 3-Carbamoyl-6-methyl-2-pyridone acid chloride (related precursor); 6-Methyl-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid chloride; 2-Oxo-6-methyl-1,2-dihydropyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 1,2-dihydro-6-methyl-2-oxo-; 6-Methyl-2-oxo-1H-pyridine-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.