Description

(3,5-Bis(Trifluoromethyl)Phenyl)(Phenyl)Methanol is a high-value fluorinated aromatic alcohol building block. This compound is critical for introducing the lipophilic and electron-withdrawing bis(trifluoromethyl)phenyl moiety into complex molecular architectures. It is primarily sought after by R&D and process development chemists in the pharmaceutical and advanced materials sectors for its utility in synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in areas targeting CNS disorders, inflammation, and oncology where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorinated aromatic system contributes to improved pest selectivity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis or as a functional group in organocatalysts, leveraging the steric and electronic properties of the bis-CF3 group.
• Advanced Material Monomer: Incorporated into polymers and liquid crystals to impart unique solubility, thermal stability, and optical properties for electronic and display applications.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic additions, and as a protected benzyl alcohol derivative in multi-step synthetic routes.

Basic Information

Product Name	(3,5-Bis(Trifluoromethyl)Phenyl)(Phenyl)Methanol
CAS No.	81390-93-4
Molecular Formula	C15H9F6O
Molecular Weight	334.22 g/mol
Synonyms	[3,5-Bis(trifluoromethyl)phenyl](phenyl)methanol; α-Phenyl-3,5-bis(trifluoromethyl)benzenemethanol; (3,5-Bis(trifluoromethyl)phenyl)(phenyl)carbinol; Benzhydrol, 3',5'-bis(trifluoromethyl)-; 3,5-Bis(trifluoromethyl)benzhydrol; 1-Phenyl-1-[3,5-bis(trifluoromethyl)phenyl]methanol
EINECS	Contact for details

Quality Control

Our (3,5-Bis(Trifluoromethyl)Phenyl)(Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.