Description

Cyclopropanecarbonyl Chloride, 1-Bromo-2,2-Dimethyl- (9Ci) is a specialized halogenated cyclopropane derivative, serving as a high-value synthetic intermediate in advanced organic synthesis. Its unique sterically hindered structure, featuring both a reactive acid chloride and a bromomethyl group, makes it a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce the cyclopropane motif—a key pharmacophore known to enhance metabolic stability and modulate biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates containing strained ring systems.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with the cyclopropane functional group for improved efficacy.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Useful for the design and synthesis of molecular probes and labeled compounds for mechanistic studies.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 1-Bromo-2,2-Dimethyl- (9Ci)
CAS No.	81359-21-9
Molecular Formula	C7H10BrClO
Molecular Weight	225.51 g/mol
Synonyms	1-Bromo-2,2-dimethylcyclopropanecarbonyl chloride; 2,2-Dimethyl-1-bromocyclopropanecarboxylic acid chloride; (1-Bromo-2,2-dimethylcyclopropyl)carbonyl chloride; 1-Bromo-2,2-dimethylcyclopropanecarboxylic acid chloride; 1-Bromo-2,2-dimethylcyclopropanecarboxyl chloride; (1-Bromo-2,2-dimethylcyclopropane)carbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 1-Bromo-2,2-Dimethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.