Description

Biotinylestrone CAS NO 81352-82-1 is a chemically modified steroid derivative, specifically a biotin-conjugated form of the natural estrogen estrone. This compound is of significant value in biochemical and pharmaceutical research as a high-affinity molecular probe. It is primarily utilized by research institutions and pharmaceutical developers engaged in hormone receptor studies, diagnostic assay development, and targeted drug delivery systems.

Application

• Research reagent for studying estrogen receptor (ER) binding and signaling pathways.
• Key intermediate in the synthesis of biotin-labeled probes for immunoassays and histochemistry.
• Development of diagnostic kits for hormone level detection.
• Tool compound in drug discovery for breast cancer and other hormone-related conditions.
• Component in affinity chromatography systems for protein purification.
• Molecular biology applications, including pull-down assays to identify receptor-interacting proteins.

Basic Information

Product Name	Biotinylestrone
CAS No.	81352-82-1
Molecular Formula	C29H40N2O4S
Molecular Weight	512.71 g/mol
Synonyms	Estrone-3-biotinyl hydrazone; Biotin-Estrone; Biotin labeled Estrone; Estrone Biotin Conjugate; 3-Hydrazono-17-oxo-1,3,5(10)-estratrien-17-yl Biotin; Biotinamidohexanoyl-Estrone Hydrazide; Biotinyl Estrone Hydrazone
EINECS	Contact for details

Quality Control

Our Biotinylestrone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.