Description

5'-Adenylic Acid Monoanhydride With (Difluorophosphonomethyl) Phosphonic Acid is a specialized nucleotide analog with a unique bisphosphonate modification. This compound matters as a high-value biochemical building block and a potent enzyme inhibitor, crucial for targeted research and development. It is primarily needed by pharmaceutical researchers, agrochemical developers, and biochemical manufacturers working on nucleotide-based therapeutics, metabolic pathway studies, and enzyme mechanism investigations.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel nucleotide-based drugs targeting metabolic disorders and bone diseases.
• Biochemical Research: Used as a potent and specific inhibitor of ATP-dependent enzymes and kinases in enzymatic studies and metabolic pathway analysis.
• Agrochemical Development: Investigated for its potential as a bioactive component in the development of new plant growth regulators or herbicides that interfere with cellular energy metabolism.
• Diagnostic Reagent Formulation: Employed in the development of specialized assay kits and diagnostic reagents for clinical and research laboratories.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in biochemistry, molecular biology, and medicinal chemistry.
• Bioconjugation & Probe Synthesis: Acts as a starting material for synthesizing labeled probes or conjugates used in imaging, detection, and targeted delivery systems.

Basic Information

Item	Detail
Product Name	5'-Adenylic Acid Monoanhydride With (Difluorophosphonomethyl) Phosphonic Acid
CAS No.	81336-78-9
Molecular Formula	C11H15F2N5O11P3
Molecular Weight	557.17 g/mol
Synonyms	Adenosine 5'-(α,β-Methylene)triphosphate, difluoromethylene analog; P1-(5'-Adenosyl) P3-[(difluorophosphono)methyl] triphosphate; Ado-5'-PP[CH2]P(O)(F)2; AMP-CPP, difluoro analog; ATPα,β-CH2,β,γ-CF2 analog; Non-hydrolyzable ATP bisphosphonate analog; 5'-Adenylyl (α,β-methylene)diphosphonate P-[(difluorophosphono)methyl] ester
EINECS	Contact for details

Quality Control

Our 5'-Adenylic Acid Monoanhydride With (Difluorophosphonomethyl) Phosphonic Acid is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are available upon request to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.