Description

4-(4-Fluorophenyl)-2-Methylbut-3-Yn-2-Ol is a specialized fluorinated organic intermediate featuring both an alkyne and a tertiary alcohol functional group. This unique molecular architecture makes it a valuable synthon for constructing more complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on new active ingredients. The compound's structure offers versatile reactivity for coupling and derivatization reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorophenyl moiety can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Sonogashira) and as a ligand precursor in organometallic chemistry due to its alkyne functionality.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	4-(4-Fluorophenyl)-2-Methylbut-3-Yn-2-Ol
CAS No.	81233-93-4
Molecular Formula	C11H11FO
Molecular Weight	178.20 g/mol
Synonyms	2-Methyl-4-(4-fluorophenyl)-3-butyn-2-ol; 4-(4-Fluorophenyl)-2-methyl-3-butyn-2-ol; 1-(4-Fluorophenyl)-2-methyl-3-butyn-2-ol; 2-Methyl-1-(4-fluorophenyl)-3-butyn-2-ol; 4-Fluorophenyl methyl butynol; 3-Butyn-2-ol, 4-(4-fluorophenyl)-2-methyl-; 2-Methyl-4-(p-fluorophenyl)-3-butyn-2-ol
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)-2-Methylbut-3-Yn-2-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.