Description

4-Methoxy Retinoic Acid is a synthetic retinoid derivative, a potent analog of retinoic acid with enhanced metabolic stability. This compound is valued for its specific biological activity and serves as a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on dermatology, oncology, and cell differentiation studies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel retinoid-based therapeutics targeting skin conditions and cancers.
• Biochemical Research: Used as a reference standard and active agent in studies of cell proliferation, differentiation, and apoptosis signaling pathways.
• Dermatological R&D: Investigated for potential applications in topical formulations aimed at treating photoaging, acne, and psoriasis.
• Cosmeceutical Research: Explored for its potential efficacy in high-end anti-aging and skin-repair cosmetic actives.
• Receptor Studies: Serves as a ligand in research focused on retinoic acid receptors (RARs/RXRs) and their functions.

Basic Information

Product Name	4-Methoxy Retinoic Acid
CAS No.	81121-20-2
Molecular Formula	C21H28O3
Molecular Weight	328.45 g/mol
Synonyms	4-Methoxyretinoic Acid; 4-Methoxy-RA; 4-Methoxy Tretinoin; 4-Methoxy all-trans-Retinoic Acid; 4-Methoxy Vitamin A Acid; 4-Methoxy-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid; 4-MeO-RA; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-4-methoxy-2,4,6,8-nonatetraenoic Acid
EINECS	Contact for details

Quality Control

Our 4-Methoxy Retinoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.