Description

1-(3,5-Di-o-Acetyl-β-D-Ribofuranosyl)-4-(1,2,4-Triazol-L-Yl)-5-Methylpyrmidin-2-One is a key nucleoside intermediate with significant importance in pharmaceutical synthesis. This compound matters for its role as a critical building block in the production of antiviral and anticancer agents, where precise molecular structure is paramount for biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of nucleoside analog therapeutics and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the research and development of drugs targeting viral polymerases and reverse transcriptases.
• Oncology Research: Serves as a building block for experimental chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Studies: Employed in enzymatic and metabolic pathway studies involving modified nucleosides.
• Fine Chemical Synthesis: Utilized in custom and contract synthesis for creating specialized libraries of bioactive molecules.
• Process Development: Acts as a reference standard and starting material for scaling up production processes in GMP environments.

Basic Information

Product Name	1-(3,5-Di-o-Acetyl-β-D-Ribofuranosyl)-4-(1,2,4-Triazol-L-Yl)-5-Methylpyrmidin-2-One
CAS No.	80991-41-9
Molecular Formula	C16H19N5O7
Molecular Weight	393.35 g/mol
Synonyms	4-(1H-1,2,4-Triazol-1-yl)-1-(3,5-di-O-acetyl-β-D-ribofuranosyl)-5-methyl-2(1H)-pyrimidinone; 1-(3,5-Di-O-acetyl-β-D-ribofuranosyl)-4-(1H-1,2,4-triazol-1-yl)-5-methylpyrimidin-2(1H)-one; 5-Methyl-4-(1,2,4-triazol-1-yl)-1-(3,5-di-O-acetyl-β-D-ribofuranosyl)pyrimidin-2(1H)-one; Ribavirin Impurity; Ribavirin Intermediate; 80991-41-9; 1-(3,5-Di-O-acetyl-β-D-ribofuranosyl)-4-(1,2,4-triazol-1-yl)-5-methyl-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can be aligned with GMP guidelines for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.