Description

2-Bromo-5-Nitrobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups—the reactive acid chloride and the electron-withdrawing nitro and bromo substituents—which enable precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs), liquid crystal materials, and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), especially those requiring a substituted benzoyl moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the nitro and bromo groups contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials, dyes, and pigments.
• Polymer & Resin Modification: Employed to introduce functional groups into polymer chains, enhancing material properties for specialty coatings and adhesives.
• Peptide & Protein Research: Can be used as an acylating agent in biochemical research for modifying amino acids or peptides.
• Organic Synthesis Reagent: A fundamental reagent for Friedel-Crafts acylation and other reactions to introduce the 2-bromo-5-nitrobenzoyl group into target molecules.

Basic Information

Product Name	2-Bromo-5-Nitrobenzoyl Chloride
CAS No.	80887-01-0
Molecular Formula	C7H3BrClNO3
Molecular Weight	264.46 g/mol
Synonyms	5-Nitro-2-bromobenzoyl chloride; 2-Bromo-5-nitrobenzoic acid chloride; Benzoic acid, 2-bromo-5-nitro-, chloride; o-Bromo-m-nitrobenzoyl chloride; 2-Brom-5-nitro-benzoylchlorid; 80887-01-0; 2-Br-5-NO2-BenzoylCl
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Nitrobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.