Description

Phloretinyl-3'-Benzylazide is a specialized chemical building block designed for advanced synthetic and research applications. This compound is valued for its azide functional group, which enables efficient click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and life science sectors for the synthesis and modification of complex molecules, including probes and drug candidates.

Application

• Click Chemistry Reagent: A key precursor for CuAAC reactions to create triazole linkages in bioconjugation and material science.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation Probe Synthesis: Enables the labeling and modification of biomolecules such as proteins, peptides, and oligonucleotides for diagnostic and therapeutic studies.
• Polymer & Material Functionalization: Serves as a modifier to introduce specific functional groups onto polymer backbones or material surfaces.
• Chemical Biology Research: Employed in activity-based protein profiling (ABPP) and the development of chemical probes to study biological pathways.
• Agrochemical Research: Acts as an intermediate in the synthesis of novel crop protection agents and plant growth regulators.

Basic Information

Product Name	Phloretinyl-3'-Benzylazide
CAS No.	80860-95-3
Molecular Formula	C22H26N4O5
Molecular Weight	426.47 g/mol
Synonyms	3'-(Azidomethyl)-4,2',4',6'-tetrahydroxydihydrochalcone; Phloretin 3'-Benzyl Azide; 1-(2,4,6-Trihydroxyphenyl)-3-(4-hydroxy-3-(azidomethyl)phenyl)propan-1-one; 3'-Azidomethylphloretin; Phloretin-3'-ylmethyl azide; Dihydrochalcone-3'-azide
EINECS	Contact for details

Quality Control

Our Phloretinyl-3'-Benzylazide is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.