Description

2-Amino-2'-o-Methyladenosine is a modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard for studying RNA modifications, enzyme mechanisms, and nucleoside-based therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, anticancer drugs, and novel molecular probes. The high-purity material is essential for ensuring the accuracy and reproducibility of sensitive biochemical assays and synthetic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for methyltransferases and other RNA-modifying enzymes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Proteomics & Genomics: Employed in research exploring epitranscriptomics, RNA methylation, and related cellular regulatory processes.
• Chemical Biology: Integral for developing molecular probes to study nucleic acid structure, function, and protein-nucleic acid interactions.
• Academic Research: Fundamental tool in university and institutional labs for investigating nucleotide metabolism and synthetic biology.

Basic Information

Product Name	2-Amino-2'-o-Methyladenosine
CAS No.	80791-87-3
Molecular Formula	C11H15N6O4
Molecular Weight	295.28 g/mol
Synonyms	2-Amino-2'-O-methyladenosine; 2'-O-Methyl-2-aminoadenosine; 2'-O-Methyladenosine, 2-amino-; 2-Amino-N6-(2'-O-methyladenosine); 2'-O-Methylisoguanosine; 2-Amino-2'-O-Me-Ado; 2'-OMe-2-aminoadenosine; 2-Aminoadenosine, 2'-O-methyl-
EINECS	Contact for details

Quality Control

Our 2-Amino-2'-o-Methyladenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.