Description

Bunazosin is a selective α-1 adrenergic receptor antagonist with significant pharmacological activity. This compound is a critical active pharmaceutical ingredient (API) and a valuable intermediate in the research and development of cardiovascular therapeutics. It is primarily utilized by pharmaceutical manufacturers, research institutions, and contract development organizations engaged in the synthesis of novel drug candidates and generic formulations. Our supply of Bunazosin CAS NO 80755-51-7 is characterized by high purity and consistent quality to support demanding applications.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of finished dosage forms for cardiovascular medications.
• Research & Development: A key reference standard and building block in preclinical and clinical studies for hypertension and benign prostatic hyperplasia (BPH).
• Process Chemistry: Serves as a crucial intermediate in the multi-step synthesis of more complex therapeutic agents.
• Analytical Standard: Used for method development, validation, and quality control testing in analytical laboratories.
• Generic Drug Manufacturing: Essential for companies developing bioequivalent versions of existing α-blocker therapies.

Basic Information

Product Name	Bunazosin
CAS No.	80755-51-7
Molecular Formula	C19H27N5O4
Molecular Weight	389.45 g/mol
Synonyms	Bunazosin; Bunazosin Hydrochloride; E-643; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine; 4-Amino-2-[4-[(tetrahydro-2-furanylcarbonyl)-1-piperazinyl]-6,7-dimethoxyquinazoline
EINECS	Contact for details

Quality Control

Our Bunazosin is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container sealed to protect the material from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.