Description

4,7-Methano-3Ah-Indene-3A-Carbonyl Chloride, Octahydro-, (3Aalpha,4Alpha,7Alpha,7Aalpha)- (9Ci) is a specialized bicyclic carbonyl chloride derivative, serving as a critical high-purity synthetic intermediate. Its value lies in its unique sterically defined structure and reactive acid chloride functionality, enabling precise chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced organic synthesis sectors, particularly for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry research targeting complex ring systems.
• Advanced Organic Synthesis: Used in the preparation of amides, esters, and ketones via nucleophilic acyl substitution reactions under controlled conditions.
• Agrochemical Research: Serves as a precursor for developing new crop protection agents with specific stereochemical requirements.
• Material Science: Potential monomer or cross-linking agent for creating polymers with tailored thermal and mechanical properties.
• Catalyst & Ligand Development: Employed in the synthesis of chiral ligands or organocatalysts due to its rigid, three-dimensional scaffold.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects requiring high-purity, structurally defined intermediates.

Basic Information

Product Name	4,7-Methano-3Ah-Indene-3A-Carbonyl Chloride, Octahydro-, (3Aalpha,4Alpha,7Alpha,7Aalpha)- (9Ci)
CAS No.	80657-63-2
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	Octahydro-4,7-methano-3aH-indene-3a-carbonyl chloride; (3aR,4S,7R,7aS)-Octahydro-4,7-methano-1H-indene-3a-carbonyl chloride; Bicyclo[2.2.1]heptane-2-carbonyl chloride derivative; endo,endo-Octahydro-4,7-methanoindene-3a-carbonyl chloride; Norbornane-derived carbonyl chloride; 3a,4,7,7a-Tetrahydro-4,7-methanoindene-3a-carbonyl chloride (stereoisomer); Contact for additional trade names.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this high-purity intermediate. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is accompanied by a comprehensive Certificate of Analysis (COA). Our rigorous testing ensures consistency and meets the exacting standards required for pharmaceutical research and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.