Description

Cationomycin is a polyether ionophore antibiotic with potent activity against Gram-positive bacteria and certain coccidia species. It functions by facilitating the transport of monovalent cations (e.g., Na⁺, K⁺) across biological membranes, disrupting cellular ion gradients and energy metabolism. This mechanism underpins its value in veterinary pharmaceuticals and agricultural research applications requiring selective antimicrobial or anticoccidial agents. Cationomycin CAS NO 80394-65-6 is widely utilized by biopharmaceutical developers, animal health manufacturers, and academic research institutions.

Application

• Veterinary feed additive for prevention and control of coccidiosis in poultry and livestock
• Research tool in ion transport studies and membrane biophysics
• Antibiotic agent in selective microbial culture media for isolating resistant strains
• Intermediate in structure–activity relationship (SAR) studies of polyether antibiotics
• Reference standard for analytical method development (HPLC, LC-MS) in regulatory testing labs
• Component in experimental formulations for topical or injectable anti-infective candidates

Basic Information

Product Name	Cationomycin
CAS No.	80394-65-6
Molecular Formula	C42H70O10
Molecular Weight	743.00 g/mol
Synonyms	Cationomycin; Monensin B; Monensin analogue B; 3′-Demethylmonensin; 3′-Desmethylmonensin; NSC-265712; CI-926; Antibiotic X-145; Monensin B (Cationomycin)
EINECS	Not listed (Notified substance under REACH; registration status: Contact for details)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches meet stringent specifications for identity, purity, and impurity profile in accordance with ACS Reagent Grade and EP/USP guidelines where applicable. Testing includes full spectral verification (IR, NMR), residual solvent analysis (GC), and heavy metals screening per ICH Q3D.

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Due to its hygroscopic nature, minimize exposure to ambient humidity and avoid repeated opening of the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 3.0% total impurities
Residue on Ignition	≤ 0.1%
Water (Karl Fischer)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.