Description

3,15,17-Trihydroxypregnan-20-One is a high-purity steroid derivative and a key intermediate in the synthesis of complex pharmaceutical compounds. Its precise stereochemistry and hydroxyl group functionality make it a valuable building block for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring high-quality, reliable intermediates for the production of steroid-based APIs and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations related to steroid hormones.
• Fine Chemical Synthesis: Employed in the preparation of more complex, functionalized steroid analogs for structure-activity relationship (SAR) studies.
• Process Development: Used in scaling up and optimizing synthetic routes for commercial pharmaceutical manufacturing.

Basic Information

Product Name	3,15,17-Trihydroxypregnan-20-One
CAS No.	80380-41-2
Molecular Formula	C21H34O4
Molecular Weight	350.50 g/mol
Synonyms	20-Oxo-3,15,17-trihydroxypregnane; 3,15,17-Trihydroxypregnan-20-one; Pregnan-20-one, 3,15,17-trihydroxy-; (3β,5β,15β,17β)-3,15,17-Trihydroxypregnan-20-one; 15β,17β-Dihydroxy-3β-hydroxypregnan-20-one
EINECS	Contact for details

Quality Control

Our 3,15,17-Trihydroxypregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.