Description

Cyclohexanecarbonyl Chloride, 4-Ethoxy-, trans- (9Ci) is a specialized organic intermediate featuring a trans-configured cyclohexane ring substituted with an ethoxy group and an acid chloride functional group. This compound matters as a high-value building block for synthesizing complex molecules, offering precise stereochemistry and reactivity for advanced chemical transformations. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals. CAS No. 80361-81-5.

Application

This high-purity intermediate is utilized in sophisticated synthetic pathways across several advanced industries.

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, or plant growth regulators where the specific stereochemistry is critical for bioactivity.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material for synthesizing chiral dopants or electron-transport materials used in display technologies.
• Advanced Polymer Chemistry: Employed in the creation of specialty polymers and dendrimers with tailored thermal or optical properties.
• Asymmetric Catalysis Ligand Synthesis: Used to construct complex, chiral ligands for metal-catalyzed asymmetric reactions.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	Cyclohexanecarbonyl Chloride, 4-Ethoxy-, trans- (9Ci)
CAS No.	80361-81-5
Molecular Formula	C9H15ClO2
Molecular Weight	190.67 g/mol
Synonyms	trans-4-Ethoxycyclohexanecarbonyl chloride; (trans)-4-Ethoxycyclohexanecarboxylic acid chloride; 4-Ethoxycyclohexanecarbonyl chloride, trans-; 4-Ethoxycyclohexanecarboxylic acid chloride, trans-; 4-Ethoxycyclohexanoyl chloride, trans-; Cyclohexanecarbonyl chloride, 4-ethoxy-, trans-; 80361-81-5 (CAS)
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonyl Chloride, 4-Ethoxy-, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water and strong bases; ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain purity and stability. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.