Description

Cyclopropanecarbonyl Chloride, 2,2,3-Trimethyl-3-(Trifluoromethyl)- (9Ci) is a specialized organofluorine building block featuring a cyclopropane ring and an acid chloride functional group. This compound matters for its role as a key intermediate in the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on novel active ingredients, where its unique sterically hindered and fluorinated structure enables the introduction of specific pharmacophores and modulates the physicochemical properties of target compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent for creating polymers with specific thermal and chemical resistance properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable reagent for introducing the cyclopropane-carbonyl moiety into complex fluorinated molecular architectures.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 2,2,3-Trimethyl-3-(Trifluoromethyl)- (9Ci)
CAS No.	80255-76-1
Molecular Formula	C8H10ClF3O
Molecular Weight	214.61 g/mol
Synonyms	2,2,3-Trimethyl-3-(trifluoromethyl)cyclopropanecarbonyl chloride; 1-(Chlorocarbonyl)-2,2,3-trimethyl-3-(trifluoromethyl)cyclopropane; Trimethyl(trifluoromethyl)cyclopropanecarbonyl chloride; Cyclopropanecarbonyl chloride, 2,2,3-trimethyl-3-(trifluoromethyl)-; 2,2,3-Trimethyl-3-trifluoromethylcyclopropane-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2,2,3-Trimethyl-3-(Trifluoromethyl)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.