Description

1-Isothiocyanato-2,3-Dimethoxy-Benzene is a specialized aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both isothiocyanate and dimethoxy functional groups, makes it a versatile reagent for constructing complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-cancer agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Heterocyclic Chemistry: Fundamental building block for constructing complex heterocycles like benzothiazoles and quinazolines via cycloaddition and condensation reactions.
• Bioconjugation and Probe Synthesis: Utilized in bioconjugate chemistry for labeling proteins and nucleic acids, and in synthesizing fluorescent probes for bioimaging.
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic or optical properties.

Basic Information

Product Name	1-Isothiocyanato-2,3-Dimethoxy-Benzene
CAS No.	80143-14-2
Molecular Formula	C9H9NO2S
Molecular Weight	195.24 g/mol
Synonyms	2,3-Dimethoxyphenyl isothiocyanate; 2,3-Dimethoxybenzene isothiocyanate; 2,3-Dimethoxyphenyl mustard oil; 1-Isothiocyanato-2,3-dimethoxybenzene; (2,3-Dimethoxyphenyl)isothiocyanate; NSC 403796; AI3-52211
EINECS	Contact for details

Quality Control

Our 1-Isothiocyanato-2,3-Dimethoxy-Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.