Description

3'-Amino-3'-Deoxyguanosine is a modified nucleoside analog of guanosine, featuring an amino group at the 3' position of the sugar moiety. This structural modification makes it a valuable building block and intermediate in the synthesis of oligonucleotides and nucleotide-based pharmaceuticals. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for antiviral and anticancer applications. The compound is supplied with a high level of purity to meet the stringent requirements of advanced biochemical research and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
• Oligonucleotide Synthesis: Used as a modified phosphoramidite or solid-support building block for creating specialized DNA/RNA sequences in research and diagnostics.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Antiviral Agent Development: Investigated for its potential to interfere with viral replication mechanisms as part of new therapeutic candidates.
• Proteomics & Genomics: Employed in the development of probes and tools for studying gene expression and protein-nucleic acid interactions.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3'-Amino-3'-Deoxyguanosine
CAS No.	80015-76-5
Molecular Formula	C10H14N6O4
Molecular Weight	282.26 g/mol
Synonyms	3'-Amino-2',3'-dideoxyguanosine; 9-[(2R,3S)-3-Amino-2-(hydroxymethyl)oxolan-3-yl]-1,9-dihydro-6H-purin-6-one; 3'-Amino-ddG; 3'-Amino-2',3'-dideoxy-Guanosine; Guanosine, 3'-amino-2',3'-dideoxy-; 3'-NH2-ddG
EINECS	Contact for details

Quality Control

Our 3'-Amino-3'-Deoxyguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.