Description

(2S)-2-Amino-3-[4-(4-Hydroxy-3-Iodo-Phenoxy)-3,5-Diiodo-Phenyl]Propanoate is a high-purity, iodinated aromatic amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a potential molecular scaffold for creating novel bioactive agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of thyroid hormone analogs, diagnostic imaging agents, and other specialized therapeutic compounds. Our supply ensures consistent quality and reliable availability for your most demanding synthesis projects.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of thyroid hormone analogs (e.g., liothyronine, thyroxine derivatives) and other iodinated bioactive molecules.
• Research Chemical: Used in biochemical and pharmacological research to study hormone-receptor interactions and metabolic pathways.
• Diagnostic Agent Precursor: Potential intermediate for developing radioiodinated compounds used in medical imaging and diagnostics.
• Chemical Biology Probe: Utilized to label or modify proteins and peptides to study structure-activity relationships.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(2S)-2-Amino-3-[4-(4-Hydroxy-3-Iodo-Phenoxy)-3,5-Diiodo-Phenyl]Propanoate
CAS No.	8065-29-0
Molecular Formula	C15H12I3NO4
Molecular Weight	674.87 g/mol
Synonyms	L-Thyroxine Impurity; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; 3,5-Diiodo-O-(4-hydroxy-3-iodophenyl)-L-tyrosine; 3,5-Diiodo-L-thyronine; T3 Derivative; Thyroxine Related Compound; L-3,5-Diiodothyronine; 3,5-T2 Precursor
EINECS	Contact for details

Quality Control

Every batch of (2S)-2-Amino-3-[4-(4-Hydroxy-3-Iodo-Phenoxy)-3,5-Diiodo-Phenyl]Propanoate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support research and cGMP-grade applications, including HPLC purity, chiral purity, and identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.