Description

Thyroxine - Triiodothyronine Combination CAS NO 8061-58-3 is a precisely formulated blend of the two primary thyroid hormones, L-Thyroxine (T4) and Liothyronine (T3), designed for pharmaceutical research and development. This combination is critical for studying thyroid hormone replacement therapy, metabolic regulation, and endocrine system function. It serves as a key active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical and biotechnology sectors developing hormone-based treatments.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of thyroid hormone replacement drugs for conditions like hypothyroidism.
• Biochemical Research: Essential tool for in-vitro and in-vivo studies on thyroid hormone action, receptor binding, and metabolic pathways.
• Reference Standard: Serves as a calibrated standard in analytical laboratories for quality control testing of thyroid medication.
• Veterinary Medicine: Used in the development of treatments for thyroid disorders in animals.
• Diagnostic Aid: Employed in the development and calibration of diagnostic assays and kits for thyroid function testing.

Basic Information

Product Name	Thyroxine - Triiodothyronine Combination
CAS No.	8061-58-3
Molecular Formula	Mixture of C15H11I4NO4 (T4) and C15H12I3NO4 (T3)
Molecular Weight	776.87 g/mol (T4), 650.97 g/mol (T3)
Synonyms	Thyroid Hormones Combination; T4-T3 Mixture; Levothyroxine and Liothyronine Combination; L-Thyroxine and Liothyronine Blend; Thyroid API Blend; 3,3',5,5'-Tetraiodo-L-thyronine and 3,3',5-Triiodo-L-thyronine; Thyroxine and Triiodothyronine API
EINECS	Contact for details

Quality Control

Our Thyroxine - Triiodothyronine Combination is manufactured under strict quality systems. Each batch is tested to ensure identity, potency, purity, and the precise ratio of T4 to T3, with specifications aligned with pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing assay results, related substances, and residual solvents is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Description	White to off-white powder
Identification (HPLC)	Conforms to reference standards
Assay (T4 Content)	Contact for details
Assay (T3 Content)	Contact for details
Ratio (T4:T3)	As per customer requirement
Related Substances (HPLC)	NMT specified limits
Loss on Drying	NMT 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.