Description

Elase CAS NO 8055-80-9 is a sterile, lyophilized preparation of two proteolytic enzymes, fibrinolysin and desoxyribonuclease, derived from bovine plasma and bovine pancreas, respectively. This combination is specifically formulated to selectively digest necrotic tissue, fibrin, and DNA-rich material without harming healthy granulation tissue. It is a critical biopharmaceutical agent for the enzymatic debridement of wounds, ulcers, and burns. This product is essential for manufacturers in the pharmaceutical, advanced wound care, and veterinary medicine sectors seeking a reliable, high-purity enzymatic component.

Application

• Pharmaceutical Manufacturing: Key active ingredient in topical ointments, creams, and solutions for enzymatic debridement.
• Advanced Wound Care: Formulation into specialized dressings for chronic wounds like venous stasis ulcers, diabetic ulcers, and pressure sores.
• Burn Treatment: Used in products designed for the non-surgical removal of eschar and necrotic tissue from second- and third-degree burns.
• Veterinary Medicine: Component in topical treatments for animal wound management and post-surgical care.
• Research & Development: Used in biochemical and pharmacological studies related to fibrinolysis, inflammation, and tissue repair mechanisms.
• Diagnostic Reagents: Potential use as a component in specialized in-vitro diagnostic kits.

Basic Information

Item	Details
Product Name	Elase
CAS No.	8055-80-9
Molecular Formula	Mixture of Enzymes
Molecular Weight	Contact for details
Synonyms	Fibrinolysin and Desoxyribonuclease; Fibrinolysin and DNase; Elase (Ointment); Fibrinolysin-Deoxyribonuclease Combination; Bovine Fibrinolysin with Bovine Desoxyribonuclease; Enzymatic Debridement Agent; Proteolytic Enzyme Mixture
EINECS	Contact for details

Quality Control

Our Elase is manufactured under strict quality systems to ensure consistency and efficacy. Each batch is tested to meet stringent specifications for enzymatic activity (units of fibrinolysin and desoxyribonuclease), sterility, and purity. We provide comprehensive Certificates of Analysis (COA) detailing assay results, microbial limits, and endotoxin levels, supporting compliance with cGMP guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C to maintain long-term stability and enzymatic activity. For short-term use, storage at 2-8°C is acceptable. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Description	Sterile, lyophilized powder or plug
Identification (IR)	Conforms to standard
Fibrinolysin Activity	≥ XXX units/vial
Desoxyribonuclease Activity	≥ XXX units/vial
pH (in solution)	6.0 - 7.5
Sterility	Sterile
Bacterial Endotoxins	< XX EU/mg
Moisture Content	< 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.