Description

Synalar N is a high-purity pharmaceutical-grade corticosteroid compound, identified by CAS No. 8025-20-5. It is a critical active pharmaceutical ingredient (API) valued for its potent anti-inflammatory and antipruritic properties. This product is essential for manufacturers in the pharmaceutical and dermatological sectors requiring a reliable, high-quality raw material for topical formulations.

Application

Synalar N (CAS 8025-20-5) is primarily utilized in the development and manufacturing of advanced topical medications. Its key applications include:

• Topical Corticosteroid Creams and Ointments: As the core API for treating inflammatory skin conditions such as eczema, psoriasis, and dermatitis.
• Dermatological Gels and Lotions: For formulations requiring precise dosing and stability in various delivery systems.
• Veterinary Pharmaceuticals: Used in topical preparations for managing skin inflammation and allergies in animals.
• Compounding Pharmacy: Serves as a key ingredient for customized medication preparations tailored to specific patient needs.
• Clinical Research: Employed as a reference standard or active component in preclinical and clinical studies for new dermatological therapies.

Basic Information

Product Name	Synalar N
CAS No.	8025-20-5
Molecular Formula	C24H31FO6
Molecular Weight	434.50 g/mol
Synonyms	Fluocinolone Acetonide; 6α,9α-Difluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; Fluocinolone Acetonide Acetate; Synalar; Fluonid; Flucort; Dermalar; Fluoderm
EINECS	Contact for details

Quality Control

Our Synalar N is manufactured under strict quality management systems to ensure it meets the stringent requirements of pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including identity, purity, and impurity profile verification against relevant pharmacopeial standards (e.g., USP, EP). A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C (59-77°F). The container should be kept in a dry, well-ventilated area. Protect from moisture and excessive heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.