Description

5-Fluoro-2'-Deoxycytidine 5'-Monophosphate is a fluorinated nucleotide analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and active metabolite in the synthesis of novel chemotherapeutic agents and antiviral drugs. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in oncology and virology programs. The high-purity material is essential for ensuring the efficacy and safety profile of downstream therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent chemotherapeutic agents, such as Capecitabine and related prodrugs.
• Antiviral Drug Research: Used in the development of nucleotide analogs targeting viral polymerases for diseases like hepatitis and HIV.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies involving DNA polymerases and related enzymes.
• Oncology Studies: Integral for in vitro and in vivo research on cell proliferation, apoptosis, and mechanism of action studies.
• Diagnostic Reagent Development: Can be used in the formulation of specialized kits for molecular diagnostics and biomarker detection.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory compliance in API manufacturing.

Basic Information

Product Name	5-Fluoro-2'-Deoxycytidine 5'-Monophosphate
CAS No.	847-22-3
Molecular Formula	C9H13FN3O7P
Molecular Weight	325.19 g/mol
Synonyms	5-Fluoro-2'-deoxycytidine 5'-(dihydrogen phosphate); 5-F-dCMP; 5-Fluoro-dCMP; 2'-Deoxy-5-fluorocytidine 5'-monophosphate; 5-Fluoro-2'-deoxycytidine monophosphate; 5-Fluorodeoxycytidine monophosphate; FdCMP; NSC 48006
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2'-Deoxycytidine 5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent controls for residual solvents and impurities. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or moisture should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	<1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.