Description

Mecamylamine Hydrochloride CAS NO 826-39-1 is a potent, non-competitive nicotinic acetylcholine receptor (nAChR) antagonist. This compound is of significant interest in research and pharmaceutical development due to its ability to cross the blood-brain barrier. It is primarily utilized by researchers in neuroscience and medicinal chemistry, as well as by manufacturers in the pharmaceutical industry for investigative and developmental purposes.

Application

• Neuroscience Research: Used as a standard tool compound to study the role of nicotinic acetylcholine receptors in the central nervous system.
• Pharmacological Studies: Employed in preclinical research to investigate autonomic ganglia blockade and its effects on blood pressure.
• Medicinal Chemistry: Serves as a key reference standard and building block in the development of novel nAChR-targeting therapeutics.
• Biochemical Assays: Utilized in in vitro receptor binding and functional assays to characterize receptor subtypes and screen for new drug candidates.
• Academic Research: A critical reagent for universities and research institutes studying neuropharmacology, addiction, and cognitive function.

Basic Information

Product Name	Mecamylamine Hydrochloride
CAS No.	826-39-1
Molecular Formula	C11H21N·HCl
Molecular Weight	203.75 g/mol
Synonyms	Mecamylamine HCl; 3-Methylaminoisocamphane Hydrochloride; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine Hydrochloride; Inversine Hydrochloride; Mecamine Hydrochloride; 1-Amino-1,2,3,3-tetramethyl-2-norbornane Hydrochloride
EINECS	212-567-8

Quality Control

Our Mecamylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.