Description

21-Dehydro Isoflupredone is a synthetic corticosteroid derivative, specifically a fluorinated prednisolone analog. This compound serves as a critical pharmaceutical intermediate in the synthesis of potent anti-inflammatory and immunosuppressive active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and research organizations engaged in the development of advanced steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced corticosteroid drugs.
• Anti-inflammatory Drug Research: Used in R&D for developing new topical and systemic anti-inflammatory agents.
• Veterinary Medicine: Potential intermediate for veterinary corticosteroid formulations.
• Biochemical Research: A reference standard in studies of steroid metabolism and receptor binding.
• Process Development: Serves as a critical intermediate in scaling up API manufacturing processes.

Basic Information

Product Name	21-Dehydro Isoflupredone
CAS No.	805-14-1
Molecular Formula	C22H27FO5
Molecular Weight	390.45 g/mol
Synonyms	9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione; 21-Dehydroisoflupredone; 9α-Fluoro-16β-methylprednisolone; Isoflupredone Acetate Related Compound; 1,4-Pregnadiene-9α-fluoro-11β,17α,21-triol-3,20-dione 16β-methyl; 9α-Fluoro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
EINECS	Contact for details

Quality Control

Our 21-Dehydro Isoflupredone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.