Description

5-Uridylic Acid, 5-Bromo-2-Deoxy-5-Fluoro-5,6-Dihydro-6-Methoxy- is a chemically modified nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and key intermediate in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular DNA replication. It is essential for research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of compounds targeting viral replication mechanisms, such as those for hepatitis and herpes viruses.
• Oncology Research: Serves as a building block for creating chemotherapeutic agents that interfere with DNA synthesis in cancer cells.
• Biochemical Research: Employed in studies of enzyme mechanisms, particularly those involving thymidylate synthase and other nucleotide-processing enzymes.
• Diagnostic Probe Development: Utilized in the creation of labeled nucleotides for molecular diagnostics and imaging.
• Process Chemistry: Acts as a specialized intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing processes.

Basic Information

Item	Detail
Product Name	5-Uridylic Acid, 5-Bromo-2-Deoxy-5-Fluoro-5,6-Dihydro-6-Methoxy-
CAS No.	800-29-3
Molecular Formula	C10H12BrFN2O7
Molecular Weight	371.12 g/mol
Synonyms	5-Bromo-2'-deoxy-5-fluorouridine 5'-(dihydrogen phosphate); 5-Bromo-5-fluoro-2'-deoxyuridine 5'-monophosphate; 5-Br-FdUMP; 5-Bromo-5-fluoro-2'-deoxyuridylic acid; 5-Bromo-5-fluoro-dUMP; 5-Bromo-5-fluoro-2'-deoxy-UMP; 2'-Deoxy-5-bromo-5-fluorouridine 5'-monophosphate; 5-Bromo-2'-deoxy-5-fluorouridine 5'-phosphate
EINECS	Contact for details

Quality Control

Our production of 5-Uridylic Acid, 5-Bromo-2-Deoxy-5-Fluoro-5,6-Dihydro-6-Methoxy- adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) documenting batch-specific results are available upon request to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.