Description

Guanosine CAS NO 85-30-3 is a purine nucleoside composed of guanine and ribose, serving as a fundamental building block for RNA and various nucleotide derivatives. Its high purity and consistent quality are critical for ensuring the reliability and reproducibility of biochemical research and pharmaceutical synthesis. This compound is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and diagnostic sectors, where it is used in nucleotide synthesis, cell culture media, and as a precursor for antiviral and anticancer drugs.

Application

• Pharmaceutical Intermediate: A key starting material in the synthesis of antiviral agents (e.g., Acyclovir, Valacyclovir) and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and molecular biology research.
• Cell Culture & Media Supplement: Incorporated into cell culture media formulations to support the growth of fastidious cell lines.
• Diagnostic Reagent Production: Serves as a raw material for manufacturing diagnostic kits and reagents used in clinical testing.
• Nucleotide & Oligonucleotide Synthesis: A vital precursor for the chemical and enzymatic production of GTP, cyclic GMP, and custom oligonucleotides.
• Food & Cosmetic Additives: Used in the production of certain flavor enhancers (5'-nucleotides) and high-end cosmetic ingredients.

Basic Information

Product Name	Guanosine
CAS No.	85-30-3
Molecular Formula	C10H13N5O5
Molecular Weight	283.24 g/mol
Synonyms	2-Amino-9-β-D-ribofuranosyl-9H-purin-6(1H)-one; 9-β-D-Ribofuranosylguanine; Guanine riboside; Vernine; G; 2-Aminoinosine; Guanin-9-yl-β-D-ribofuranoside
EINECS	201-590-2

Quality Control

Our Guanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can supply grades compliant with in-house specifications, with the capability to meet USP, EP, or other relevant pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water (Karl Fischer)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%
Specific Rotation	-60° to -70° (c=1 in 0.1N NaOH)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.