Description

Dexpanthenol CAS NO 81-13-0 is the biologically active alcohol analog of pantothenic acid (Vitamin B5), a vital coenzyme precursor. This high-purity compound is essential for its superior moisturizing, healing, and anti-inflammatory properties, making it a cornerstone ingredient in advanced formulations. It is primarily sought by manufacturers in the pharmaceutical, high-end personal care, and nutraceutical industries for its proven efficacy in skin barrier repair and cellular regeneration.

Application

• Pharmaceutical Formulations: A key active ingredient in topical ointments, creams, and sprays for wound healing, burn treatment, and the management of skin irritations, ulcers, and dermatoses.
• Cosmetic & Personal Care: Widely used in moisturizers, anti-aging serums, body lotions, hair conditioners, and shampoos for its deep hydrating, soothing, and skin barrier-strengthening effects.
• Medical Device Coatings: Incorporated into coatings for wound dressings, catheters, and other implantable materials to promote tissue compatibility and healing.
• Nutraceuticals & Dietary Supplements: Utilized in solid and liquid supplement formulations to support pantothenic acid supplementation, contributing to energy metabolism and skin health from within.
• Veterinary Products: Employed in topical preparations for animal care to aid in the healing of cuts, abrasions, and hot spots.
• Ophthalmic Solutions: Used in eye drops and lubricants to relieve dry eye symptoms and support corneal epithelial repair.

Basic Information

Product Name	Dexpanthenol
CAS No.	81-13-0
Molecular Formula	C9H19NO4
Molecular Weight	205.25 g/mol
Synonyms	D-Panthenol; Dexpanthenol; D-Pantothenyl Alcohol; Provitamin B5; Pantothenol; (+)-Panthenol; Panthenol; D-Pantothenate; (R)-Panthenol; (2R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
EINECS	201-327-3

Quality Control

Our Dexpanthenol is manufactured under strict quality management systems. We offer grades compliant with major pharmacopoeial standards, including USP-NF and EP, ensuring suitability for pharmaceutical and high-grade cosmetic applications. Every batch undergoes rigorous analytical testing, including HPLC for assay and purity, to guarantee identity, potency, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to slightly yellowish, viscous liquid
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0%
Specific Rotation	+29.0° to +31.5°
Refractive Index	1.495 - 1.502
pH (5% solution)	9.5 - 10.5
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.