Description

11Alpha-Hydroxyprogesterone is a key steroid intermediate with significant importance in pharmaceutical synthesis. This compound serves as a crucial precursor in the production of various corticosteroid and progestogen-based active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of steroid hormones. Our supply ensures high purity and consistent quality to meet the stringent demands of advanced pharmaceutical manufacturing.

Application

• Pharmaceutical Intermediate: A vital building block in the multi-step synthesis of corticosteroid drugs such as hydrocortisone and its derivatives.
• Progestogen Synthesis: Used as a starting material or intermediate in the production of various progestogen compounds for hormonal therapies.
• Research & Development: Employed in biochemical and pharmacological research to study steroid metabolism and receptor interactions.
• API Manufacturing: Integral to the commercial-scale production of steroid-based Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Reference Standard: Serves as a high-purity analytical reference standard for quality control laboratories in the pharmaceutical industry.

Basic Information

Product Name	11Alpha-Hydroxyprogesterone
CAS No.	80-75-1
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	11α-Hydroxyprogesterone; 11α-Hydroxypregn-4-ene-3,20-dione; 11α-OH-P; 11α-Hydroxy-4-pregnene-3,20-dione; 11α-Hydroxydihydroprogesterone; 11α-Hydroxyprogestone
EINECS	201-305-5

Quality Control

Our 11Alpha-Hydroxyprogesterone is produced and tested to meet high-purity standards suitable for pharmaceutical applications. Each batch undergoes rigorous analytical testing, including HPLC for assay and related substances, to ensure consistent quality and compliance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to a robust quality management system to guarantee traceability and reliability for our global B2B customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. For long-term storage, consider using a desiccant in the storage area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.