Description

2',3'-Dideoxy-5'-o-Dmt-Cytidine is a key nucleoside derivative, specifically a DMT-protected cytidine analog with a dideoxy sugar moiety. This compound is of critical importance as a sophisticated building block in the synthesis of oligonucleotides and modified nucleic acids, enabling advanced research and therapeutic development. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on antisense technology, prodrug development, and the creation of novel nucleotide-based therapeutics.

Application

• Oligonucleotide Synthesis: Serves as a vital phosphoramidite precursor for the solid-phase synthesis of modified DNA/RNA strands.
• Antisense & Antiviral Research: Used in the development of nucleoside analogs targeting viral replication and genetic diseases.
• Prodrug Development: Acts as an intermediate for creating cytidine-based prodrugs with enhanced cellular uptake and stability.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies involving polymerases and nucleoside kinases.
• Pharmaceutical Intermediates: A crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Diagnostic Probe Development: Utilized in the creation of labeled nucleotide probes for diagnostic assays and imaging.

Basic Information

Item	Details
Product Name	2',3'-Dideoxy-5'-o-Dmt-Cytidine
CAS No.	797804-87-6
Molecular Formula	C30H31N3O6
Molecular Weight	529.59 g/mol
Synonyms	5'-O-(4,4'-Dimethoxytrityl)-2',3'-dideoxycytidine; 5'-O-DMT-2',3'-ddC; DMT-2',3'-ddCyd; 1-[(2R,5S)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-2-yl]-4-amino-2-pyrimidinone; 2',3'-Dideoxy-5'-O-(4,4'-dimethoxytrityl)cytidine; N4-Benzoyl-5'-O-DMT-2',3'-dideoxycytidine (protected form); ddC DMT Ester
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxy-5'-o-Dmt-Cytidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports applications requiring high-purity, well-characterized building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider desiccants and an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.