Description

5-Fluoro-4'-C-Methylcytidine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of nucleoside-based drugs targeting viral replication and cellular proliferation.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced nucleoside analog prodrugs and active pharmaceutical ingredients (APIs).
• Antiviral Research: Investigated for its potential activity against a range of RNA and DNA viruses, serving as a core structure for novel antiviral agents.
• Oncology Research: Used in the development of chemotherapeutic agents designed to inhibit cancer cell growth by interfering with nucleic acid synthesis.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand polymerase mechanisms and nucleotide metabolism.
• Prodrug Development: Acts as a precursor molecule for the design of prodrugs with enhanced bioavailability and targeted delivery.

Basic Information

Product Name	5-Fluoro-4'-C-Methylcytidine
CAS No.	791585-24-5
Molecular Formula	C10H14FN3O5
Molecular Weight	275.24 g/mol
Synonyms	4'-C-Methyl-5-fluorocytidine; 5-Fluoro-4'-C-methylcytidine; 1-((2R,3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 4'-C-Methyl-5-fluoro-cytidine; 5-Fluoro-1-((2R,3R,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4'-C-Methylcytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.