Description

2-[Ethyl[3-[[4-[[1-[2-[(3-Fluorophenyl)Amino]-2-Oxoethyl]-1H-Pyrazol-4-Yl]Amino]Quinazolin-7-Yl]Oxy]Propyl]Amino]Ethyl Dihydrogen Phosphate is a sophisticated, high-purity chemical intermediate designed for advanced research and pharmaceutical development. This compound is critical for its role as a key building block in the synthesis of targeted therapeutic agents, particularly in oncology. It is essential for pharmaceutical companies, biotechnology research institutions, and advanced chemical synthesis laboratories focused on developing novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel, targeted anti-cancer agents and kinase inhibitors.
• Biochemical Research: Used as a reference standard and active probe in enzymatic studies and cellular pathway analysis.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry programs aiming to optimize drug potency and selectivity.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex, high-value active pharmaceutical ingredients.
• Preclinical Studies: Utilized in the formulation of compounds for in vitro and in vivo pharmacological testing.

Basic Information

Product Name	2-[Ethyl[3-[[4-[[1-[2-[(3-Fluorophenyl)Amino]-2-Oxoethyl]-1H-Pyrazol-4-Yl]Amino]Quinazolin-7-Yl]Oxy]Propyl]Amino]Ethyl Dihydrogen Phosphate
CAS No.	786685-53-8
Molecular Formula	C28H33FN7O6P
Molecular Weight	613.58 g/mol
Synonyms	2-({Ethyl[3-({4-[(1-{2-[(3-Fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-4-yl)amino]quinazolin-7-yl}oxy)propyl]amino}ethyl) dihydrogen phosphate; N-[3-({4-[(1-{2-[(3-Fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-4-yl)amino]quinazolin-7-yl}oxy)propyl]-N-ethyl-2-phosphonooxyethanaminium; (2-{Ethyl[3-({4-[(1-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-4-yl)amino]quinazolin-7-yl}oxy)propyl]amino}ethyl) dihydrogen phosphate; A phosphonooxy derivative of a quinazolinyl-pyrazole inhibitor intermediate.
EINECS	Contact for details

Quality Control

This high-value intermediate is manufactured under strict quality management systems to ensure batch-to-batch consistency and purity suitable for research and development. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.