Description

1H-Pyrrole-2-Carbonyl Chloride, 4-Amino-1-Propyl- (9Ci) is a specialized heterocyclic building block featuring both an amino group and a highly reactive acid chloride functionality. This compound matters for its role as a key intermediate in the synthesis of complex molecules, enabling the formation of amide bonds under mild conditions. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of functional polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the creation of labeled compounds and activity-based probes for studying biological pathways.
• Peptidomimetic Chemistry: Facilitates the incorporation of pyrrole motifs into peptide backbones to enhance stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	1H-Pyrrole-2-Carbonyl Chloride, 4-Amino-1-Propyl- (9Ci)
CAS No.	780034-31-3
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	4-Amino-1-propyl-1H-pyrrole-2-carbonyl chloride; 1-Propyl-4-amino-pyrrole-2-carboxylic acid chloride; 4-Amino-1-propyl-pyrrole-2-carboxylic acid chloride; 1H-Pyrrole-2-carbonyl chloride, 4-amino-1-propyl-; 780034-31-3; 4-Amino-1-propyl-1H-pyrrole-2-carbonyl chloride; 1-Propyl-4-aminopyrrole-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carbonyl Chloride, 4-Amino-1-Propyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance for sensitive synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.