Description

1-Azabicyclo[2.2.0]Hexane-4-Carbonyl Chloride (9Ci) is a specialized bicyclic organic compound featuring a strained ring system and a highly reactive acid chloride functional group. This unique structure makes it a critical building block for the synthesis of complex nitrogen-containing heterocycles, particularly in advanced pharmaceutical research. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel β-lactam analogs and other strained heterocyclic compounds with potential biological activity.
• Agrochemical Research: Used to create new pesticidal and herbicidal agents by incorporating its unique bicyclic framework.
• Ligand Synthesis: Serves as a starting material for preparing specialized ligands used in catalysis and medicinal chemistry.
• Peptidomimetic Chemistry: Employed to introduce constrained, bicyclic motifs into peptide backbones to enhance stability and bioavailability.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new chemical space in organic synthesis laboratories.
• Fine Chemical Production: Used in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	1-Azabicyclo[2.2.0]Hexane-4-Carbonyl Chloride (9Ci)
CAS No.	779285-68-6
Molecular Formula	C6H8ClNO
Molecular Weight	145.59 g/mol
Synonyms	1-Azabicyclo[2.2.0]hexane-4-carbonyl chloride; 4-(Chlorocarbonyl)-1-azabicyclo[2.2.0]hexane; 1-Azabicyclo[2.2.0]hexane-4-carboxylic acid chloride; Bicyclo[2.2.0]hexane-4-carbonyl chloride, 1-aza-; 4-Carboxy-1-azabicyclo[2.2.0]hexane chloride
EINECS	Contact for details

Quality Control

Our production of 1-Azabicyclo[2.2.0]Hexane-4-Carbonyl Chloride adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.