Description

3-Pyridinecarbonyl Chloride, 2-Amino-5-Nitro- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel materials. Its unique structure, featuring both an acid chloride and nitro-amino substitution, makes it a versatile intermediate for constructing pyridine-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the pyridine core is a key pharmacophore.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Precursor: Acts as an intermediate in the synthesis of complex organic dyes and functional pigments.
• Material Science: Utilized in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biochemical research.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 2-Amino-5-Nitro- (9Ci)
CAS No.	776234-73-2
Molecular Formula	C7H4ClN3O3
Molecular Weight	213.58 g/mol
Synonyms	2-Amino-5-nitro-3-pyridinecarbonyl chloride; 2-Amino-5-nitronicotinoyl chloride; 5-Nitro-2-aminonicotinoyl chloride; 3-Pyridinecarbonyl chloride, 2-amino-5-nitro-; 2-Amino-5-nitro-pyridine-3-carbonyl chloride; Nicotinoyl chloride, 2-amino-5-nitro-; (2-Amino-5-nitropyridin-3-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.