Description

3-(Hydroxymethyl)Sulphur Pentafluoride, also known as 3-(Pentafluorosulphanyl)Benzyl Alcohol, is a high-value organofluorine building block characterized by the unique pentafluorosulfanyl (SF5) group, which imparts exceptional lipophilicity, metabolic stability, and electronic properties. This compound is critical for medicinal chemistry and advanced materials research, enabling the synthesis of novel bioactive molecules and functional polymers. It is primarily sought by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers developing next-generation products with enhanced performance profiles.

Application

• Pharmaceutical Intermediates: A key synthon for introducing the metabolically robust SF5 moiety into drug candidates, potentially improving their pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the SF5 group can enhance biological activity and environmental stability.
• Liquid Crystal & Electronic Materials: Serves as a precursor for functionalized aromatics used in liquid crystal displays (LCDs) and organic electronic components due to its strong dipole moment and polarizability.
• Polymer Modification: Incorporated into polymer backbones to create specialty materials with unique surface properties, chemical resistance, or tailored refractive indices.
• Catalyst & Ligand Development: Employed in the design of novel ligands for catalysis, leveraging the steric and electronic influence of the SF5 group.
• R&D & Chemical Libraries: A valuable compound for building diverse screening libraries in high-throughput discovery programs across multiple industries.

Basic Information

Item	Details
Product Name	3-(Hydroxymethyl)Sulphur Pentafluoride, 3-(Pentafluorosulphanyl)Benzyl Alcohol
CAS No.	773872-71-2
Molecular Formula	C7H5F5OS
Molecular Weight	232.17 g/mol
Synonyms	3-(Hydroxymethyl)phenylsulfur pentafluoride; 3-(SF5)Benzyl Alcohol; (3-(Pentafluoro-λ6-sulfanyl)phenyl)methanol; 3-(Pentafluorosulfanyl)benzenemethanol; 3-(SF5)C6H4CH2OH; α-(Pentafluorosulfanyl)-m-tolyl alcohol
EINECS	Contact for details

Quality Control

Our production of 3-(Pentafluorosulphanyl)Benzyl Alcohol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive R&D and scale-up applications. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.