Description

4-(2-Fluorophenyl)Benzyl Alcohol is a versatile fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty materials, where the fluorine atom and benzyl alcohol moiety impart unique physicochemical properties. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and liquid crystal industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine substituent can enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in display technologies, improving dielectric anisotropy and response times.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for more efficient and stable OLED devices.
• Polymer Modification: Acts as a monomer or chain terminator to introduce fluorinated phenyl groups into polymers, altering their surface properties and chemical resistance.
• Cross-Coupling Reactions: The benzyl alcohol group can be transformed into various functionalities, making it a valuable substrate in Suzuki, Heck, and other palladium-catalyzed couplings.

Basic Information

Product Name	4-(2-Fluorophenyl)Benzyl Alcohol
CAS No.	773872-57-4
Molecular Formula	C13H11FO
Molecular Weight	202.22 g/mol
Synonyms	2-Fluoro-4'-(hydroxymethyl)biphenyl; [1,1'-Biphenyl]-4-methanol, 2'-fluoro-; 4-(2-Fluorophenyl)benzenemethanol; (4-(2-Fluorophenyl)phenyl)methanol; 2'-Fluoro[1,1'-biphenyl]-4-methanol; 4-(2-Fluorobenzyl)phenol (tautomer); α-(4-(2-Fluorophenyl)phenyl)methanol
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)Benzyl Alcohol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) with detailed specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.