Description

[5-Bromo-2-(Difluoromethoxy)Phenyl]Methanol is a high-value, multi-functional aromatic alcohol derivative, distinguished by its bromine and difluoromethoxy substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used as a precursor for developing new-generation herbicides and fungicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: The bromine and alcohol functionalities make it a valuable starting material for creating specialized ligands and organocatalysts.
• Material Science Research: Employed in the synthesis of monomers and functionalized polymers for advanced materials with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.
• Academic & Industrial R&D: Serves as a research chemical for exploring new organic reactions and methodologies in medicinal and process chemistry.

Basic Information

Product Name	[5-Bromo-2-(Difluoromethoxy)Phenyl]Methanol
CAS No.	773868-62-5
Molecular Formula	C8H7BrF2O2
Molecular Weight	253.04 g/mol
Synonyms	(5-Bromo-2-(difluoromethoxy)phenyl)methanol; 5-Bromo-2-(difluoromethoxy)benzyl alcohol; [5-Bromo-2-(difluoromethoxy)phenyl]methanol; 2-(Difluoromethoxy)-5-bromobenzyl alcohol; Benzyl alcohol, 5-bromo-2-(difluoromethoxy)-; 773868-62-5; 5-Bromo-2-difluoromethoxybenzyl alcohol
EINECS	Contact for details

Quality Control

Our production of [5-Bromo-2-(Difluoromethoxy)Phenyl]Methanol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP-compliant practices and traceability ensures reliability for your most demanding R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.