Description

5-Pyrimidinecarbonyl Chloride, 2-Amino-4-Methoxy- (9Ci) is a high-purity, reactive heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical acylating agent, enabling the efficient introduction of a functionalized pyrimidine scaffold into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Serves as a precursor for labeling reagents and activity-based probes used in proteomics and target identification studies.
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical suppliers offering bespoke synthesis services for complex heterocycles.

Basic Information

Product Name	5-Pyrimidinecarbonyl Chloride, 2-Amino-4-Methoxy- (9Ci)
CAS No.	773798-35-9
Molecular Formula	C6H6ClN3O2
Molecular Weight	187.58 g/mol
Synonyms	2-Amino-4-methoxypyrimidine-5-carbonyl chloride; 2-Amino-4-methoxy-5-pyrimidinecarbonyl chloride; 4-Methoxy-2-aminopyrimidine-5-carboxylic acid chloride; 5-(Chlorocarbonyl)-4-methoxy-2-aminopyrimidine; 2-Amino-4-methoxypyrimidine-5-carboxylic acid chloride; 4-Methoxy-2-aminopyrimidine-5-carbonyl chloride; (2-Amino-4-methoxypyrimidin-5-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarbonyl Chloride, 2-Amino-4-Methoxy- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and impurity profiles. We adhere to cGMP principles where applicable to support our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (DMF, DMSO, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.