Description

Benzoyl Chloride, 3-(Aminomethyl)-4-Fluoro- (9Ci) is a specialized fluorinated benzoyl chloride derivative featuring a reactive aminomethyl substituent. This compound is a high-value pharmaceutical intermediate and organic synthesis building block, prized for its ability to introduce both a benzoyl group and a functionalized amine handle into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Peptide Mimetics & Conjugation: The reactive benzoyl chloride and aminomethyl groups facilitate the creation of peptide-like structures and bioconjugates.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and functionalized surfaces.
• Ligand & Catalyst Development: Employed in the synthesis of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) in medicinal chemistry due to its specific fluorine substitution pattern.

Basic Information

Item	Details
Product Name	Benzoyl Chloride, 3-(Aminomethyl)-4-Fluoro- (9Ci)
CAS No.	771573-07-0
Molecular Formula	C8H7ClFNO
Molecular Weight	187.60 g/mol
Synonyms	4-Fluoro-3-(aminomethyl)benzoyl chloride; 3-(Aminomethyl)-4-fluorobenzoyl chloride; (3-Aminomethyl-4-fluorophenyl)methanone chloride; 4-Fluoro-3-aminomethylbenzoyl chloride; 771573-07-0; Benzoyl chloride, 3-(aminomethyl)-4-fluoro-
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 3-(Aminomethyl)-4-Fluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.