Description

Cyclohexanecarbonyl Chloride, 4-Amino- (9Ci) CAS NO 763036-24-4 is a specialized organic intermediate featuring both an amino group and an acid chloride functional group on a cyclohexane ring. This unique bifunctional structure makes it a versatile and valuable building block for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries seeking to introduce the 4-aminocyclohexanecarbonyl moiety into target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the cyclohexane scaffold provides stability and bioactivity.
• Peptide Mimetics & Conjugation: The reactive acid chloride group enables efficient coupling to amines, making it useful for creating peptide analogs or conjugating pharmacophores to carriers.
• Polymer Modification: Serves as a monomer or cross-linking agent for specialty polymers, imparting specific mechanical or chemical resistance properties.
• Ligand & Catalyst Development: Employed in the preparation of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Used to synthesize advanced organic materials, such as liquid crystals or organic semiconductors, with tailored electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services for clients requiring bespoke chemical entities.

Basic Information

Item	Detail
Product Name	Cyclohexanecarbonyl Chloride, 4-Amino- (9Ci)
CAS No.	763036-24-4
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	4-Aminocyclohexanecarbonyl chloride; 4-Aminocyclohexanoyl chloride; trans-4-Aminocyclohexanecarboxylic acid chloride; 4-Aminocyclohexanecarboxylic acid chloride; 4-Amino-1-cyclohexanecarbonyl chloride; (4-Aminocyclohexyl)carbonyl chloride; 4-Aminocyclohexylcarbonyl chloride; 1-Cyclohexanecarbonyl chloride, 4-amino-
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarbonyl Chloride, 4-Amino- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO 9001 standards where required, ensuring the material is suitable for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.