Description

2,2-Difluoro-2-(4-Fluorophenyl)Ethanol is a high-value fluorinated alcohol building block, essential for introducing difluoroethanol motifs into complex molecular architectures. Its unique structure, featuring both aromatic and aliphatic fluorine atoms, makes it a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the difluoro group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Polymer Modification: Employed to introduce fluorine into polymer side chains, altering surface properties, chemical resistance, and stability.
• Organic Synthesis & Catalysis: A versatile reagent in academic and industrial research for constructing complex, fluorinated organic molecules.
• Fluorinated Surfactant Precursor: Can be utilized in the synthesis of specialty surfactants with unique wetting and leveling properties.

Basic Information

Product Name	2,2-Difluoro-2-(4-Fluorophenyl)Ethanol
CAS No.	762292-74-0
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	2,2-Difluoro-2-(4-fluorophenyl)ethan-1-ol; 4-Fluorophenyl-2,2-difluoroethanol; 1-(4-Fluorophenyl)-2,2-difluoroethanol; α,α-Difluoro-4-fluorobenzeneethanol; 2,2-Difluoro-1-(4-fluorophenyl)ethanol; (4-Fluorophenyl)difluoromethyl carbinol
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-2-(4-Fluorophenyl)Ethanol is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, is performed to guarantee identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom specifications to meet your specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.