Description

4-Ethoxy-2,3-Difluorobenzoylchloride is a high-purity, reactive organic intermediate belonging to the class of substituted benzoyl chlorides. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing difluorinated aromatic ether motifs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the ethoxy-difluoro substitution pattern confers specific biological activity.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce fluorinated aromatic units into polymers, enhancing their thermal stability and chemical resistance.
• Organic Synthesis Reagent: Functions as an acylating agent in Friedel-Crafts and other coupling reactions to introduce the 4-ethoxy-2,3-difluorobenzoyl group into target molecules.
• Material Science Research: Utilized in the creation of advanced organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Ethoxy-2,3-Difluorobenzoylchloride
CAS No.	761459-04-5
Molecular Formula	C9H7ClF2O2
Molecular Weight	220.60 g/mol
Synonyms	2,3-Difluoro-4-ethoxybenzoyl chloride; 4-Ethoxy-2,3-difluorobenzoic acid chloride; Benzoic acid, 4-ethoxy-2,3-difluoro-, chloride; 761459-04-5; 4-Ethoxy-2,3-difluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2,3-Difluorobenzoylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.