Description

2H-Pyran-4-Carbonyl Chloride, 4-Aminotetrahydro- (9Ci) is a high-purity, reactive chemical intermediate featuring a unique fused heterocyclic structure. This compound is valued for its dual functionality, combining a reactive acid chloride group with a protected amino group, making it a versatile building block for complex organic synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular scaffolds and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its heterocyclic core can contribute to biological activity.
• Chemical Research & Development: Serves as a critical building block in academic and industrial labs for synthesizing complex heterocyclic compounds, libraries for screening, and novel materials.
• Peptide Mimetic & Conjugate Chemistry: The reactive carbonyl chloride group enables efficient coupling reactions to create peptide-like structures or conjugate the heterocycle to other molecular entities.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or organic frameworks with tailored properties.

Basic Information

Product Name	2H-Pyran-4-Carbonyl Chloride, 4-Aminotetrahydro- (9Ci)
CAS No.	761340-01-6
Molecular Formula	C7H10ClNO2
Molecular Weight	175.61 g/mol
Synonyms	4-Aminotetrahydro-2H-pyran-4-carbonyl chloride; Tetrahydro-4-amino-2H-pyran-4-carbonyl chloride; 4-Aminotetrahydro-2H-pyran-4-carboxylic acid chloride; 4-Aminooxane-4-carbonyl chloride; 761340-01-6; 4-Amino-tetrahydro-pyran-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-4-Carbonyl Chloride, 4-Aminotetrahydro- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and other relevant analytical techniques, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.